Update on HBV and HIV Coinfection: Pathogenesis and Treatment
نویسنده
چکیده
dr. dieterich began his november 2005 lecture acknowledging that the etiology and pathogenesis of hepatitis B virus (hbv) infection are extremely complex. “hbv is a very complicated organism,” he explained. “In some ways it is like hiv, but in many ways it’s not. And it has even less in common with the hepatitis C virus. Hepatitis C is relatively straightforward and can be cured, whereas hepatitis B is a very sneaky virus and is much more difficult to eliminate. This kind of uncertainty can be very hard for clinicians to grasp.”
منابع مشابه
Understanding the pathogenesis and management of hepatitis B/HIV and hepatitis B/hepatitis C virus coinfection.
The approach to the hepatitis B virus (HBV)-infected patient who is also infected with HIV or hepatitis C virus (HCV) is very different from the approach to the patient with only one virus infection. HBV/HIV coinfection is common. Agents that have dual activity against HBV and HIV should be considered as treatment of choice in combination regimens in HBV/HIV-coinfected patients beginning antire...
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Background: HBV and HCV coinfection is common, particularly in endemic areas and among high risk groups. In this study we have investigated the prevalence of HBV/HCV coinfection and compared the biochemical and serological characteristics of such patients compare with the patients having hepatitis C infection alone. Methods: We studied 207 patients diagnosed as having chronic hepatitis C, with ...
متن کاملThe pathogenesis of liver disease in the setting of HIV-hepatitis B virus coinfection.
There are many potential reasons for increased liver-related mortality in HIV-hepatitis B virus (HBV) coinfection compared with either infection alone. HIV infects multiple cells in the liver and might potentially alter the life cycle of HBV, although evidence to date is limited. Unique mutations in HBV have been defined in HIV-HBV-coinfected individuals and might directly alter pathogenesis. I...
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Background and Objective: The drug resistance mutations are key elements in the failure of long-term treatment of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections. The mutation in the YMDD motif in the P gene of HBV is the most critical factor in antiviral drug (especially lamivudine) resistance. This study aimed to assess the YMDD motif and other polymerase gene mutati...
متن کاملHBV-HIV Coinfection: Key Clinical Management Issues
Given the shared risk factors for transmission, coinfection with hepatitis B virus (HBV) and HIV is common. HIV infection increases the risk of chronic HBV infection and hastens the progression of liver disease in patients with chronic HBV infection. The treatment of chronic HBV infection needs to be carefully coordinated with HIV management in HBV-HIV coinfected patients. The main goals of tre...
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تاریخ انتشار 2006